Fall 2024 Course Offerings
| MSCI 811 |
Microbiology, Immunology and Biochemistry Journal Club (MIB JC) |
Ae-Kyung Yi |
| Time:Wednesday at noon-1pmPlace:201A, MSBDuration:18 meeting/yr, 60 min. |
Credit:1 |
| Discuss and analyze pertinent issues, trends, policies, practices, and processes in the current developments in biomedical sciences (focus on Microbiology, Immunology and Biochemistry) and scholarship. (didactic, seminar)
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| MSCI 910 |
Student Seminar |
David Nelson |
| Time:Place:Duration:
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Credit:3 |
| Reports of current research are made by students for fellows and staff. Presentations are followed by general informal discussion. Under certain circumstances, topics of current interest in the field are selected and reviewed by students and staff members. (didactic, lecture)
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| MSCI 931 |
Immunity and Inflammation |
Elizabeth A Fitzpatrick |
| Time:Place:Duration:
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Credit:3 |
| This is an amended proposal for the MSCI 931 Immunity and Inflammation course. This course will provide a comprehensive overview of resistance to infection and immunity to microbial pathogens. The lectures will present in detail the molecular genetic, structural and cellular mechanisms that determine innate and adaptive immune cell activation and effector function. The literature reviews will use papers to document research that has elucidated innate and adaptive immune mechanisms that determine host resistance to infection. At the end of the course it is expected that students will have a comprehensive and fundamental understanding of the concepts that govern host-pathogen interactions. (didactic, lecture)
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| MSCI 935 |
Techniques II - Methods for Nucleic Acids |
Martha Howe |
| Time:Place:Duration:
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Credit:2 |
| The theory and practical application of commonly used techniques for working with nucleic acids are considered, including nucleic acid isolation, quantitation, and electrophoresis; hybridization, mini-and micro arrays; DNA sequencing; oligonucleotide synthesis, uses, PCR and qPCR; restriction and modification enzymes, and polymerases; prokaryotic and eukaryotic cloning vectors; library construction and clone detection; cDNA-expression and siRNA-silencing libraries; making transgenic mice; in vitro mutagenesis, gel retardation, footprinting, and chromatin assays. (hybrid, lecture)
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Spring 2025 Course Offerings
| MSCI 800 |
Master's Thesis and Research |
David Nelson |
| Time: Place: Duration: |
Credit: variable |
| Research performed under the direction and supervision of the respective student's advisor, in partial fulfillment of the requirements for the degree of Master of Science (didactic, lecture)
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| MSCI 811 |
Microbiology, Immunology and Biochemistry Journal Club (MIB JC) |
Ae-Kyung Yi |
| Time: Wednesday at noon-1pm Place: 201A, MSB Duration: 18 meeting/yr, 60 min. |
Credit: 1 |
| Discuss and analyze pertinent issues, trends, policies, practices, and processes in the current developments in biomedical sciences (focus on Microbiology, Immunology and Biochemistry) and scholarship. (didactic, seminar)
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| MSCI 814 |
Bioinformatics I |
David Nelson |
| Time: 2:30-4:50 Place: GEB B107 Duration: Thursday |
Credit: 2 |
| This course consists of eleven 2.5-hour segments. The material will be introduced in a brief lecture format for 30-45 minutes as necessary. The majority of time will be spent using computer applications of bioinformatics tools. The course is designed to provide practical training in bioinformatics methods including accessing the major public sequence databases, using the five BLAST tools to find sequences, analyzing protein and nucleic acid sequences, detecting motifs or domains in proteins, assembling protein sequences from genomic DNA, detecting exons and finding intron-exon boundaries, aligning sequences (Clustal W), and making phylogenetic trees (Phylip). Basic proteomics methods and comparative genomics will also be discussed. Students should leave the course with a working knowledge of how to carry out research using these tools. (didactic, lecture)
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| MSCI 815 |
Bioinformatics II |
David Nelson |
| Time: 2:30-4:50 Place: GEB B107 Duration: Thursday |
Credit: 1 |
| This course consists of six 2.5-hour segments partially as lecture and partially as computer tutorial sessions to demonstrate advanced bioinformatics methods and the use of databases. The course follows Bioinformatics I. Topics include knowledge base mining; 3D structure viewers like Cn3D, the VAST databases of 3D structure alignments; use of genome browsers like UCSC and Ensembl and NCBI's genomic biology section; gene arrays--their construction, use, and data analysis; mapping quantitative trait loci (QTLs) and radiation hybrid mapping; genome assembly and annotation. (hybrid, lecture)
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| MSCI 840-003 |
Special Topics in Molecular Sciences - Replication of RNA Viruses |
David Nelson |
| Time: Place: Duration: |
Credit: variable |
| Directed readings or special course in topics of current interest. (didactic, lecture)
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| MSCI 910 |
Student Seminar |
Ae-kung Yi |
| Time: Place: Duration: |
Credit: 3 |
| Reports of current research are made by students for fellows and staff. Presentations are followed by general informal discussion. Under certain circumstances, topics of current interest in the field are selected and reviewed by students and staff members. (didactic, lecture)
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| MSCI 930 |
Molecular and Cellular Basis of Pathogenesis |
Lorraine Albritton |
| Time: 9-10:30 Place: GEB A310 Duration: MWF |
Credit: 3 |
| The course will provide a comprehensive overview of both viral and bacterial pathogenesis from the perspective of both host and pathogen. The lectures are intended to complement the immunology and pathophysiology lectures in IP 842 "Systems Biology" to provide a comprehensive and fundamental understanding of the concepts that govern host-pathogen interactions. Lectures will present in detail the molecular genetic, structural, and cellular mechanisms that viral and bacterial pathogens use to infect cells and tissues of the host and the subsequent disease consequences of infection. (didactic, lecture)
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| MSCI 934 |
Techniques I - Biochemical and Cellular Methods |
Terry Cooper |
| Time: Place: Duration: |
Credit: 2 |
| The theory and practical application of commonly used techniques in biochemistry, cell biology, immunology, and structural biology are considered, including absorption and emission spectroscopy; multiple chromatographic methods for use both with and without tags; protein purification strategies; protein electrophoresis and blotting; mass spectroscopy and proteomics; NMR and X-ray crystallography; generation and use of monoclonal and polyclonal antibodies; flow cytometry; light, fluorescence, and confocal microscopy; apoptosis and cell purification. (hybrid, lecture)
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